More severe covid: The University of Oxford discovered that a higher-risk form of the gene hinders the cells lining the airways and lungs from effectively responding to the virus.
Researchers discovered a gene in. Covid-19 that doubles the risk of respiratory failure, which could help explain why some ethnic groups are more prone to severe disease than others.
More severe covid: The University of. Oxford discovered that a higher-risk form of the gene hinders the cells lining the airways and lungs from effectively responding to the virus. According to the study released. Thursday, 60 percent of people with South Asian ancestry had this variant of the gene, compared to 15 percent of persons with European ancestry.
The findings may explain why particular groups across the Indian subcontinent have witnessed greater rates of illness and death. Many other factors, such as socioeconomic conditions, play a role. According to the scientists, therefore the gene cannot be used as a sole explanation. Despite the virus’s enormous impact on persons of Afro-Caribbean descent, just 2% of them have the higher-risk genotype.
Vaccination, which remains the greatest form of protection for people with the gene, known as. LZTFL1, might be especially beneficial, according to the scientists. Although no tailored medications are now available. The findings open the possibility of research into treatments particular to patients with this gene.
This “shows how important the lung’s response to infection is,” according to. James Davies, co-lead author and associate professor of genomics at Oxford, who worked in intensive care during the pandemic. “This is significant because most treatments have centered on altering the immune system’s response to the virus.”
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